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نوع الوثيقة |
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مقال في مجلة دورية |
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عنوان الوثيقة |
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PREVALENCE OF ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPES I AND II AMONG SAUDI ARABIAN BLOOD DONORS PREVALENCE OF ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPES I AND II AMONG SAUDI ARABIAN BLOOD DONORS |
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لغة الوثيقة |
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الانجليزية |
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المستخلص |
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In 1980 and 1982, Gallo et al. described the isolation of
human T-cell lymphotropic virus type I (HTLV-I)1 and
type II (HTLV-II).2 In the majority of cases, infection with
these viruses does not cause diseases. However, HTLV-I
infection has been etiologically associated with neoplastic
diseases3 and a variety of demyelinating neurologic
disorders.4-5 The association of HTLV-II with leukemia
pathogenesis is not well established,6 however, some cases
of neurological disease have been reported.7
HTLV-I infection may be transmitted via blood
transfusion. Cellular blood components transmit the virus
with 20%-63% efficiency.8,9 Among recipients of HTLV-Icontaminated
blood components, the mean interval from
infection to antibody seroconversion is 40 days (range, 20-
90 days).9,10
The transmission of HTLV-II via blood transfusion has
been documented.11 HTLV-I is now recognized to occur
worldwide, although it is characteristically endemic in
Japan, the Caribbean, Southern Italy, New Guinea, Africa,
and the Seychelles,12 as well as in several countries in the
Middle East.13-14
In the present study, we took sera from volunteer Saudi
blood donors and hemodialysis patients over a three-year
period to determine the prevalence of HTLV-I/II among
Saudi blood donors, and to examine the cost effectiveness
of HTLV screening in Saudi blood banks |
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ردمد |
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0256-4947 |
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اسم الدورية |
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Annals of Saudi Medicine |
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المجلد |
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20 |
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العدد |
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2 |
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سنة النشر |
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1421 هـ
2000 م |
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نوع المقالة |
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مقالة علمية |
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تاريخ الاضافة على الموقع |
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Monday, August 31, 2009 |
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الباحثون
| سعاد الجاعوني | Al-Jaouni, Soad | باحث | دكتوراه | |
|