Document Details

Document Type : Thesis 
Document Title :
Studies on some enteric becteria (enter bacterieae) associated with patients in Makkah Al Mukkarmah
دراسات علي البكتريا المعوية فصيلة ENTEROBACTERIACEAE المصاحبة للمرضي بمكة المكرمة
 
Subject : Biological 
Document Language : Arabic 
Abstract : A total of 9007 samples from in patients attending Al-Noor Specialist Hospital, Makkah Al-Mukarramah were examined to study. the epidemiology a:nd antibiotics sensitivity of Enterobacteriaceae family, during the period 1412-1413H .13.3% were found positive on culture, out of which 29.7% belonged to the Enterobacteriaceae family. Among the positive samples of this family, 157"were isolated from urine, 69 from blood, 63 from wounds and 68 from the miscellaneous sources. The highest percentage found in nursery followed by me-dical ward. The percentage of E.coli and Klebsiella isolated was 35.6 and 33.6 respectively. The isolates from community acquired infection (C.A.I) showed high percentage (52.4) than the hospital acquircd in.{ection (H.A.I) (47.6) .In urine samples, urinary tract infection (U. T.I) isolates were more in female cases than the male cases and E.coli was found the most common organism. In blood culture samples, Klebsiella gave thc highest percentage of bacteraemia and H.A.I was more than C.A.I .Thc mortality in bacteraemia was 43.5% especially in children less than one year. In wounds samples, E.coli and Klebsiella were found to be the most common organism and both having 27% and H.A.I (61.9%) was more than (C.A.I) (38.1%) .In miscellaneous sources infections, Klebsiella was found to be at ighest percentage (32.4), where C.A.I (60.3) was more than H.A.I (39.7). By using disc diffusion method the effect of 8 antibiotics was tested on the bacteria isolated from urine. It was found that Nalidixic acid, Norfloxacin and Gentamicin were the best antibio~cs for urinary isolates. The effect of 15 antibiotics on the bacteria isolated from blood, wounds and miscellaneous sources, showed high sensitivity to lmipenem and Amikacin .On the other hand, the genera of this family were highly resistant to Ampicillin. The isolates from hospital showed high resistance to most antibiotics than that of community. MIC of antibiotics to bacterial growth was estimated by using 8 antibiotics from common groups of antibiotics. The results of MIC90% decreased in case of Norfloxacin, Cefoxitin and increased in case. of Ampicillin, CWoramphenicol and Tetracycline. Klebsiella and Enterobacter isolates showed increased the MIC90% to the most antibiotics. The bacteria isolated from blood samples showed more resistance to antibiotics than that isolated from-other sources .~ 
Supervisor : Dr. Mohamed Kamal El Din Ashayeb 
Thesis Type : Master Thesis 
Publishing Year : 1418 AH
1997 AD 
Co-Supervisor : Prof. Saad Brki Almasaudi 
Added Date : Thursday, June 12, 2008 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
فايز حبيب الرحمن حافظHafez, Faiz Habib AL-RahmanResearcherMaster 

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