Document Details

Document Type : Article In Journal 
Document Title :
HISTO PATHOLOGICAL EFFECT OF METOCLOPRAMIDE ON THE RENAL TISSUS OF CHICK EMBRYO
التأثير المرضي لعقار الميثوكلوبراميد على أنسجة كلية جنين الدجاج
 
Subject : HISTO PATHOLOGICAL EFFECT OF METOCLOPRAMIDE ON THE RENAL TISSUS OF CHICK EMBRYO 
Document Language : English 
Abstract : The present investigation shows the renal histopathological effects of metoclopramide, which is an antiemetic drug, on 10-day chick embryos. 0.2 mg or 0.4 mg of this drug was injected after 24, 48 or 72 hours of incubation in groups of fifty eggs of Arbor acre aggs. These groups of eggs together with control groups injected with an equivalent amount of sterilized distilled water were examined after 10 days of incubation. The living ones were serially sectioned, stained, processed and microscopically examined to detect any deviation in the renal structure. It was found that metoclopramide had profound histopathological effects on the renal tissues of the treated embryos. The size of the kidney as a whole greatly decreased. The Malpighian corpuscles, renal tubules and ducts, and the collecting tubules decreased in number and size. The renal tissues degenerated and their individual cells deteriorated. All these features increased with the increase of the given dose and the earlier the age of the treated embryos . 
ISSN : 215-219 
Journal Name : Egypt J. Histol. 
Volume : 7 
Issue Number : 2 
Publishing Year : 1404 AH
1984 AD 
Article Type : Article 
Added Date : Thursday, February 26, 2009 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
منى فريد عبدالرحمنAbduAlRahman, Mona FaridInvestigatorDoctorate 
سلوى محمد قيطةQuata, Salwa MohammedResearcherDoctoratedoctorsalwa@gmail.com

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