Document Details

Document Type : Article In Journal 
Document Title :
PREVALENCE OF ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPES I AND II AMONG SAUDI ARABIAN BLOOD DONORS
PREVALENCE OF ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPES I AND II AMONG SAUDI ARABIAN BLOOD DONORS
 
Document Language : English 
Abstract : In 1980 and 1982, Gallo et al. described the isolation of human T-cell lymphotropic virus type I (HTLV-I)1 and type II (HTLV-II).2 In the majority of cases, infection with these viruses does not cause diseases. However, HTLV-I infection has been etiologically associated with neoplastic diseases3 and a variety of demyelinating neurologic disorders.4-5 The association of HTLV-II with leukemia pathogenesis is not well established,6 however, some cases of neurological disease have been reported.7 HTLV-I infection may be transmitted via blood transfusion. Cellular blood components transmit the virus with 20%-63% efficiency.8,9 Among recipients of HTLV-Icontaminated blood components, the mean interval from infection to antibody seroconversion is 40 days (range, 20- 90 days).9,10 The transmission of HTLV-II via blood transfusion has been documented.11 HTLV-I is now recognized to occur worldwide, although it is characteristically endemic in Japan, the Caribbean, Southern Italy, New Guinea, Africa, and the Seychelles,12 as well as in several countries in the Middle East.13-14 In the present study, we took sera from volunteer Saudi blood donors and hemodialysis patients over a three-year period to determine the prevalence of HTLV-I/II among Saudi blood donors, and to examine the cost effectiveness of HTLV screening in Saudi blood banks 
ISSN : 0256-4947 
Journal Name : Annals of Saudi Medicine 
Volume : 20 
Issue Number : 2 
Publishing Year : 1421 AH
2000 AD
 
Article Type : Article 
Added Date : Monday, August 31, 2009 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
سعاد الجاعونيAl-Jaouni, Soad ResearcherDoctorate 

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