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Document Details
Document Type
:
Article In Journal
Document Title
:
“Frequency of satellite cells in perisynaptic versus extrasynaptic regions of the rat soleus muscle”
“Frequency of satellite cells in perisynaptic versus extrasynaptic regions of the rat soleus muscle”
Document Language
:
English
Abstract
:
Whether satellite cell nuclei are more common in the vicinity of motor endplates than in extrasynaptic regions of rat muscle is not clear. If this were true, then perisynaptic satellite cells could play a role in the preservation of the endplate. We compared the frequency of satellite cell nuclei in the perisynaptic and extrasynaptic regions of rat soleus muscle. An absolute as well as a relative increase of perisynaptic satellite cells was found. The mean frequency of satellite cell nuclei per sarcomere was 0.016 in perisynaptic regions and 0.002 in extrasynaptic regions (P=0.01). Also, perisynaptic satellite cells had many processes, and some features suggested a more active state. It was suggested that satellite cells might add to the pool of junctional myonuclei which synthesize acetylcholine receptor molecules, or help in the repair of the postsynaptic membrane. Alternatively, they may synthesize basal lamina components which are specific for the endplate.
ISSN
:
1059-7794
Journal Name
:
Al-Azhar Medical Journal
Volume
:
32
Issue Number
:
4
Publishing Year
:
2003 AH
2003 AD
Article Type
:
Article
Added Date
:
Sunday, March 28, 2010
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
شريف حسن
Hassan, Sherif
Researcher
Doctorate
Files
File Name
Type
Description
26221.1
1
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