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Document Type |
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Article In Conference |
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Document Title |
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CLINICAL, RADIOGRAPHIC AND BIOCHEMICAL EVALUATION OF A LYOPHILIZED INORGANIC BOVINE CANCELLOUS BONE XENOGRAFT AND BIORESORBABLE COLLAGEN MEMBRANE IN THE MANAGEMENT OF PERIODONTAL INTRAOSSEOUS DEFECTS تقييم إكلينيكي وأشعى وكميائى حيوى لاستخدام بدائل الظم المجففة الغير عضوية شبكية الشكل وغشاء كولاين قابل للتحلل في علاج عيوب الأسنان العظيمة |
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Document Language |
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English |
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Abstract |
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The present study was conducted to evaluate clinically, radiographically and biochemically two
regenerative approaches used for the management of interproximal periodontal defects in chronic
periodontitis (CP) patients. Twenty periodontal osseous defe<;tsof matched severity, in 10 systemically
healthy CP patients, were selected for the study. They were divided into two groups of ten defects each:
Group I treated with a combination of resorbable collagen membrane (Gen-Oerm)@ and lyophilized
inorganic cancellous bovine bone graft (Gen-Ox) @; and Group II managed by using the bone graft alone
(Gen-Ox) @. Prior to surgery, patients were placed on an oral hygiene program; scaling and root planning
were performed. At b.aseline, and at six and nine months postoperatively, the plaque (PI) and papillary
bleeding index (PSI), probing pocket depth (PPO), and clinical attachment level (CAL), as well as
standardized periapical radiographs were recorded. Linear and densitometric analysis of the radiographs
were done. A significant improvement was seen in all clinical parameters in the two studied groups, when
compared to baseline. No significant differences were noted between the studied groups for any of the
clinical variables studied. Radiographic and densitometric analysis revealed that the two modalities
resulted in significant increase in alveolar bone height and decrease in radiographic optical density, with
no statistical difference between the groups. Concerning the biochemical assessment, gingival crevicular
fluid (GCF) samples were collected from each patient at the surgical site at baseline, 3, 6 and 9 months
postoperatively. Filter papers were inserted at the surgical site, and mean levels of total sulfated
glycosaminoglycans (GAGs) and of chondroitin sulfate (CS) were determined using an Alcian blue dye
detection system. The mean levels of CS and total sulfated GAGs in GCF significantly decreased in both
groups at 3 months, then levels began to rise throughout the study period revealing better results in the
combination group. |
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Conference Name |
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الاسكندرية الدولي الرابع عشر لطب الاسنان |
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Publishing Year |
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1424 AH
2004 AD |
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Article Type |
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Article |
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Added Date |
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Tuesday, October 19, 2010 |
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Researchers
| غادة منصور | Mansour, Ghada | Researcher | Doctorate | |
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