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Document Type |
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Article In Journal |
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Document Title |
: |
CLINICAL, HISTOLOGICAL AND DENSITOMETRIC STUDY OF THE EFFECT OF A BISPHOSPHONATE (ETIDRONATE) ON BONE REPAIR IN DOGS دراسة اكلينيكية وهستولودجية وبالكثافة الضوئية لتأثير مادة البيسفوسفونات على اصلاح العظام في الكلاب |
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Document Language |
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English |
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Abstract |
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The effect of Etidronate disodium, a bisphosphonate, on repair of osseous defects was evaluated
clinically, histologically and radiographically. Eight adult dogs were used in this study: 4 constituted
the experimental group, and 4 the control group. In all animals, mucoperiosteal flaps were
elaborated and matched bilateral interproximal osseous defects were induced. Animals of the experimental
group were injected subcutaneously with Etidronate sodium 3 days each week, while controls
received 0.9% NaCI. The drug administration started immediately after surgery and for 8
weeks. Clinical measurements of plaque index, gingival index and attachment level were recorded at
baseline,l and 2 months post-operatively. Periapical radiographs were taken at baseline and 2
months for densitometric analysis. The animals were sacrificed at 2 months post-surgically, and the
mandibles were processed for histology. Etidronate-treated group revealed promotion of periodontal
healing, when compared to controls, as evidenced clinically by improved attachment level, histologically
by parameters pf periodontal regeneration, and radiographically by reduced optical density. |
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ISSN |
: |
0 |
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Journal Name |
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Egyptian Dental Journal |
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Volume |
: |
45 |
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Issue Number |
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4 |
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Publishing Year |
: |
1419 AH
1999 AD |
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Article Type |
: |
Article |
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Added Date |
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Tuesday, October 19, 2010 |
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Researchers
| غادة منصور | Mansour, Ghada | Researcher | Doctorate | |
|